Creating Waves of Awareness
Asthma and Homoeopathy
Definitions- Clinical Definition- Pathological Definition- Prevalence- Mortality- Pathophysiology- Alterations In Airway Constitutive Cells- Infiltration By Inflammatory Cells- Alterations Of The Noncellular Component Of The Airway Wall- Clinical Presentation- Acute Asthma- Exercise-Induced Asthma- Allergen-Induced Asthma- Virus-Induced Asthma- Aspirin-Induced Asthma- Acute Severe Asthma- Chronic Stable Asthma- Physical Examination- Vital Signs- Thoracic Examination- Laboratory Findings- Pulmonary Function Testing- Airway Responsiveness Testing- Arterial Blood Gases- Other Findings In The Blood- Radiographic Findings- Electrocardiographic Findings- Sputum Findings- Treatment
Asthma is a clinical syndrome defined physiologically by episodic reversible airway narrowing (Psora) and hyperresponsiveness of the airways to a variety of stimuli (Tubercular).
It is defined pathologically by the presence of certain recognizable microscopic features including infiltration of the airways with eosinophils (Psora), hypertrophy and hyperplasia of airway smooth muscle (Sycosis), hypertrophy and hyperplasia of mucous secretory apparatus (Sycosis), and overall thickening of the airway wall (Sycosis).
It affects men and women equally. The prevalence of asthma below age 20 is greater than that above age 20.
Mortality rates from asthma are difficult to estimate because of the difficulty of establishing asthma as the cause of death.
Alterations in Airway Constitutive Cells
Infiltration by Inflammatory Cells
Alterations of the Noncellular Component of the Airway Wall
Individuals who exercise for brief periods of time, on the order of 15 to 20 min, commonly develop airway obstruction after the cessation of exercise. Obstruction usually begins 5 to 10 min after the completion of exercise and resolves in 1 to 4 hrs.
It results from the direct effects of mediators released from inflammatory cells as a consequence of clustering of IgE receptors on the surface of effector cells (Psora). Common allergens inducing asthma are cat allergen (Fel D1), house dust mite allergen (der P1), and tree and grass pollens.
Many individuals with a history of asthma will be relatively asymptomatic until they contract a viral illness, when asthma may occur without other known inciting stimuli.
Approximately 1% to 10% of patients with moderate-to-severe asthma have aspirin-induced asthma, which consists of symptoms of moderately severe airway obstruction, rhinorrhea, sneezing, tearing, dermal changes, and, in some patients, GI changes (cramping, nausea, or vomiting).
Acute Severe Asthma
Acute severe asthma is a more severe and prolonged version of an acute asthmatic episode.
Chronic Stable Asthma
Chronic stable asthma is the name given to the syndrome characterized by episodes of asthmatic symptoms and airflow obstruction that recur.
Patients with asthma have tachypnea (Psora), with respiration rates often 25 to 40 breaths/min, accompanied by tachycardia (Psora), with pulse rates of about 100 as well as pulsus paradoxus (Sycosis), an exaggerated inspiratory fall in the systolic blood pressure (Psora).
During an acute attack of asthma, the chest is hyperinflated (Psora), which can be appreciated on inspection. Percussion of the thorax demonstrates hyperresonance (Sycosis), with loss of the normal variation in dullness from diaphragmatic movement (Tubercular). The cardinal physical finding in asthma is wheezing (Sycosis). Wheezing is commonly heard during both inspiration and expiration; it tends to be louder during expiration.
Pulmonary Function Testing
Decreased airflow rates throughout the vital capacity are the most common pulmonary function abnormality in mild asthma.
Airway Responsiveness Testing
Airway responsiveness testing measures the bronchoconstrictor response elicited by a standard stimulus.
Arterial Blood Gases
For a patient with a mild attack of asthma, the PaO2 is usually between 55 and 75, and the PaCO2 between 25 and 35.
Other Findings in the Blood
Blood eosinophilia on the order of 4% to 8% is common. Elevated serum levels of IgE are often used as an index of the atopic state. Specific radiooligosorbent tests (RAST) can be conducted to determine the amount of IgE specifically directed against an offending antigen.
Severe cases of asthma can be associated with elevated serum concentrations of aminotransferases, lactate dehydrogenases, muscle creatinine phosphokinase, transcarbamylase, and antidiuretic hormone. Furthermore, therapy with b-adrenergic agonists, may create low serum potassium levels.
In most cases, chest radiographs in patients with asthma are normal. Complications of severe asthma include pneumomediastinum and pneumothorax, which may be detected only radiographically.
In most cases of asthma, the electrocardiogram is remarkable only for sinus tachycardia. In severe attacks right axis deviation, right bundle branch block, P pulmonale, or even ST-T wave abnormalities may occur.
Between acute asthma attacks, in the absence of infection, the sputum of patients with asthma is usually clear. During an acute asthma attack, even without infection, the sputum may be green to yellow from eosinophil peroxidase. Asthmatic findings include eosinophils, Charcot-Leyden crystals (crystallized eosinophil lysophospholipase), Curschmann's spirals (bronchiolar casts composed of mucus and goblet cells), or Creola bodies (clusters of airway epithelial cells with identifiable, quite often beating, cilia).
ars > sulph.> nux-v. > calad. > nat-s. > lach. > carb-v. > ip. > lob. > sil. etc. are the most similar remedies for asthmatic pathology. Otherwise, the similimum remedy must be chosen as per Homoeopathic doctrine.
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