Posted on November 26, 2009 at 12:30am
Several epidemiological studies provide support for the “hygiene hypothesis”, which suggest that a cleaner environment and fewer childhood infections cause the increase in allergic diseases.
The developing immune system apparently requires microbial exposure in early life to stimulate Th1 lymphocytes. The relative absence of microbes thereby favors the development of Th2-driven responses, which is associated with allergic diseases. Recent studies have shown that markers of poor… Continue