There are over 200 comments, some serious with a medical approach, others post smart-alec answers. Here are some of the comments:
Myostatin-related muscle hypertrophy?
Aseptic meningitis after a coxsackie virus, common in kids, with residual encephalitis and got type I diabetes and now just has neurodegenerative effects from that whole infection
defect in the myostatin gene or a naturally occurring 'null' to that gene like the double muscled whippet is Sally's problem
cerebral palsy. maybe a virus set off both her DM-I and some type of meningitis with residual CP. and I am sure they already looked for pituitary and adrenal tumors in the other woman? It's like an odd variant of Cushings.